Endocrine Abstracts

Introduction: Pheochromocytomas and paragangliomas (PPGLs) exhibit an up to 20% malignancy rate. Various clinical, genetic, and pathological features have been proposed as predictors of malignancy. However, until present there are no robust indices to reliably predict metastatic PPGLs.Aim: The aim of the present study was to prospectively validate the value of methoxytyramine as risk marker of metastatic disease and establish a machine learning (ML) mode...

The recreational use of cannabis is becoming more widespread since many countries, including parts of Europe, are currently discussing legalisation. Moreover, the medical use of cannabinoids is already established and has many indications such as multiple sclerosis-induced spasticity or supportive therapy in the case of tumour-associated pain or loss of weight or appetite. However, the effects of cannabinoids on tumour growth still remain largely unexplored in many tumour enti...